Modafinil 400 mg is an approved prescription drug which enhances wakefulness in adult patients suffering from some types of sleep-wake disorders. The conditions under which modafinil is medically indicated include excessive daytime sleepiness due to narcolepsy, sleep apnea, and shift work sleep disorder. Modafinil has various effects on the neurochemical processes in the brain which help stimulate wakefulness, but its mechanism is still not well known.

The dosage of 400 mg per day is rather significant and may not be proper for all patients. The recommended dose is selected depending on the specific condition, individual tolerability, medical history, and other drugs being used. The patient should not increase the dose independently.

Side effects of the drug may include such symptoms as headache, nausea, dizziness, nervousness, anxiety, dry mouth, and insomnia. Modafinil interacts with some medications and decreases the contraceptive effect of hormonal contraceptives. Very rare cases of severe skin reactions and allergies need prompt medical care.

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